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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Thiouracil
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
  • Nucleic Acid, Nucleoside, or Nucleotide
Preferred_Name
  • Thiouracil
NSC_Code
  • 19473
UMLS_CUI
  • C0039957
CAS_Registry
  • 141-90-2
FDA_UNII_Code
  • 59X161SCYL
Contributing_Source
  • FDA
Chemical_Formula
  • C4H4N2OS
Legacy_Concept_Name
  • Thiouracil
CHEBI_ID
  • CHEBI:348530
FULL_SYN
  • THIOURACILPTFDA59X161SCYL
  • ThiouracilPTNCI
DEFINITION
  • A sulfur-containing uracil. An established antithyroid drug and highly selective inhibitor of nitric oxide synthase (NOS), thiouracil also covalently binds to dopaquinone, produced by tyrosinase catalyzed oxidation of tyrosine, thereby selectively accumulating in de novo-synthesized melanin in overactive melanin-producing cells and providing a means to localize melanoma cells. (NCI04)NCI
code
  • C29856
sameAs
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