About: HLA Class II Histocompatibility Antigen DRB     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • HLA Class II Histocompatibility Antigen DRB
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Immunologic Factor
Preferred_Name
  • HLA Class II Histocompatibility Antigen DRB
UMLS_CUI
  • C1333901
Legacy_Concept_Name
  • HLA_Class-II_Histocompatibility_Antigen-DRB
FULL_SYN
  • HLA Class II Histocompatibility Antigen DRBPTNCI
DEFINITION
  • HLA class II DR beta chain proteins (26-28 kD) form heterodimers with alpha (DRA) chains, both anchored in the membrane. Expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages), alpha/beta heterodimers present peptides derived from extracellular proteins. Hundreds of DRB alleles have been described and typing for these polymorphisms is done for transplantation. (NCI)NCI
code
  • C29573
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