About: Urea     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Urea
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Urea
NSC_Code
  • 34375
UMLS_CUI
  • C0041942
CAS_Registry
  • 57-13-6
FDA_UNII_Code
  • 8W8T17847W
Contributing_Source
  • FDA
ALT_DEFINITION
  • A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.MSH2002_06_01
  • A substance formed by the breakdown of protein in the liver. The kidneys filter carbamide out of the blood and into the urine. Carbamide can also be made in the laboratory. A topical form of carbamide is being studied in the treatment of hand-foot syndrome (pain, swelling, numbness, tingling, or redness of the hands or feet that may occur as a side effect of certain anticancer drugs).NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 40286
PDQ_Closed_Trial_Search_ID
  • 40286
Chemical_Formula
  • CH4N2O
Legacy_Concept_Name
  • Carbamide
CHEBI_ID
  • CHEBI:16199
FULL_SYN
  • UREAPTFDA8W8T17847W
  • UREASYDTPNSC0034375
  • ureaPTNCI-GLOSSCDR0000471785
  • UreaPTDCP05047
  • UreaPTNCI
  • UreaphilSYDTPNSC0034375
  • VanamideBRNCI
  • UreaphilBRNCI
  • Aqua CareBRNCI
  • Elaqua XXBRNCI
  • CarbamideBRNCI
  • NutraplusBRNCI
  • carbamidePTNCI-GLOSSCDR0000572226
  • LanaphilicBRNCI
DEFINITION
  • A nitrogenous compound containing a carbonyl group attached to two amine groups with osmotic diuretic activity. In vivo, urea is formed in the liver via the urea cycle from ammonia and is the final end product of protein metabolism. Administration of urea elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including the brain, cerebrospinal fluid and eye, into interstitial fluid and plasma, thereby decreasing pressure in those tissues and increasing urine outflow.NCI
code
  • C29531
sameAs
http://linked.open...y/mesh/hasConcept
is sameAs of
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 25 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software