About: Tolterodine Tartrate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Tolterodine Tartrate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Tolterodine Tartrate
UMLS_CUI
  • C0719805
CAS_Registry
  • 124937-52-6
FDA_UNII_Code
  • 5T619TQR3R
Contributing_Source
  • FDA
Chemical_Formula
  • C22H31NO.C4H6O6
Legacy_Concept_Name
  • Tolterodine
CHEBI_ID
  • CHEBI:32245
FULL_SYN
  • TOLTERODINE TARTRATEPTFDA5T619TQR3R
  • DetrolBRNCI
  • Tolterodine TartratePTNCI
  • DetrusitolBRNCI
DEFINITION
  • The tartrate salt form of tolterodine, a benzhydryl compound and a muscarinic receptor antagonist possessing both antimuscarinic and antispasmodic properties. Both tolterodine and its active metabolite, 5-hydroxymethyltolterodine, competitively blocks muscarinic receptors, thereby inhibiting acetylcholine receptor binding. This antagonistic action results in an increase in residual urine, reflecting an incomplete emptying of the bladder, and a decrease in detrusor pressure, indicating an antimuscarinic action on the lower urinary tract.. The 5-hydroxymethyl metabolite appears to contribute significantly to the therapeutic effects.NCI
code
  • C29504
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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