About: Terbinafine Hydrochloride

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Terbinafine Hydrochloride
rdfs:subClassOf	ANTIFUNGALS
Has_Free_Acid_Or_Base_Form	TERBINAFINE
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Antibiotic Organic Chemical
Preferred_Name	Terbinafine Hydrochloride
UMLS_CUI	C0771029
CAS_Registry	78628-80-5
FDA_UNII_Code	012C11ZU6G
Contributing_Source	FDA
Chemical_Formula	C21H25N.HCl
Legacy_Concept_Name	Terbinafine_Hydrochloride
FULL_SYN	Terbinafine HydrochloridePTNCI (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine HydrochlorideSNNCI TERBINAFINE HYDROCHLORIDEPTFDA012C11ZU6G LamisilBRNCI SF 86-327CNNCI
DEFINITION	A synthetic allylamine derivative structurally related to naftifine, antifungal Terbinafine Hydrochloride blocks ergosterol biosynthesis by inhibition of squalene epoxidase, part of the sterol synthesis pathway for the fungal cell membrane. Highly lipophilic, it tends to accumulate in skin, nails, and fatty tissues. Terbinafine is active against dermatophytes. (NCI04)NCI
code	C29492
sameAs	TERBINAFINE HYDROCHLORIDE
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0398072
is Has_Salt_Form of	TERBINAFINE
is sameAs of	TERBINAFINE HYDROCHLORIDE TERBINAFINE HYDROCHLORIDE

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