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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Temazepam
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Temazepam
NSC_Code
  • 246303
UMLS_CUI
  • C0039468
CAS_Registry
  • 846-50-4
FDA_UNII_Code
  • CHB1QD2QSS
Contributing_Source
  • FDA
Chemical_Formula
  • C16H13ClN2O2
Legacy_Concept_Name
  • Temezepam
FULL_SYN
  • OxydiazepamSYNCI
  • 10-chloro-4-hydroxy-6-methyl-2-phenyl-3,6-diazabicyclo[5.4.0]undeca-2,8,10,12-tetraen-5-oneSNNCI
  • TEMAZEPAMPTFDACHB1QD2QSS
  • Ro 5-5345CNNCI
  • TemazepamPTNCI
DEFINITION
  • A benzodiazepine derivative with antidepressant, sedative, hypnotic and anticonvulsant properties. Temazepam potentiates the inhibitory activities of gamma-aminobutyric acid (GABA) by binding to the GABA receptor, located in the limbic, neocortical and mesencephalic reticular system. This increases the frequency of chloride channel opening events, allowing the flow of chloride ions into the neuron leading to membrane hyperpolarization and decreases neuronal excitability.NCI
code
  • C29488
sameAs
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