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AttributesValues
rdf:type
rdfs:label
  • Tazarotene
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Tazarotene
UMLS_CUI
  • C0288792
CAS_Registry
  • 118292-40-3
Accepted_Therapeutic_Use_For
  • Topical treatment of facial acne vulgaris; stable plaque psoriasis; mitigation (palliation) of facial fine wrinkling; facial mottled hyper- and hypopigmentation; benign facial lentigines
FDA_UNII_Code
  • 81BDR9Y8PS
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used on the skin to treat several skin conditions. It is also being studied in the treatment of basal cell skin cancer and basal cell nevus syndrome. Tazarotene is related to vitamin A and is made in the laboratory. It turns on a gene that may help stop the growth of skin cancer cells. Tazarotene is a type of synthetic retinoid.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 553530
PDQ_Closed_Trial_Search_ID
  • 553530
Chemical_Formula
  • C21H21NO2S
Legacy_Concept_Name
  • Tazarotene
CHEBI_ID
  • CHEBI:32184
FULL_SYN
  • tazarotenePTNCI-GLOSSCDR0000559445
  • TazarotenePTDCP20325
  • AvagePTNCI-GLOSSCDR0000589422
  • AvageBRNCI
  • TazoracPTNCI-GLOSSCDR0000589421
  • TazoracBRNCI
  • Ethyl 6-(2-(4,4-Dimethylthiochroman-6-yl)ethynyl)nicotinateSNNCI
  • TAZAROTENEPTFDA81BDR9Y8PS
  • AGN-190168CNNCI
  • 6-[(3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl]- 3-Pyridinecarboxylic Acid, Ethyl EsterSNNCI
  • TazarotenePTNCI
DEFINITION
  • A synthetic, topical retinoid. Tazarotene induces the expression of tazarotene-induced gene 3 (TIG3), a tumor suppressor gene. In psoriasis, tazarotene normalizes abnormal keratinocyte differentiation and reduces their hyperproliferation. (NCI04)NCI
code
  • C29487
sameAs
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