About: Risperidone     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Risperidone
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Risperidone
UMLS_CUI
  • C0073393
CAS_Registry
  • 106266-06-2
FDA_UNII_Code
  • L6UH7ZF8HC
Contributing_Source
  • FDA
Chemical_Formula
  • C23H27FN4O2
Legacy_Concept_Name
  • Risperidone
CHEBI_ID
  • CHEBI:8871
FULL_SYN
  • RisperidonePTNCI
  • RISPERIDONEPTFDAL6UH7ZF8HC
DEFINITION
  • A benzisoxazole derivative with antipsychotic property. Risperidone selectively antagonizes serotonin (5-HT) effects via cortical 5-HT2 receptor, and, to a lesser extent, competes with dopamine at the limbic dopamine D2 receptor. The antagonism leads to decreased psychotic effects, such as hallucinations and delusions. In addition, risperidone has low to moderate affinity for histamine H1, 5-HT1A, 5-HT1C, and 5-HT1D receptors, while it has weak affinity for dopamine D1 and haloperidol-sensitive sigma site receptors.NCI
code
  • C29416
sameAs
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