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AttributesValues
rdf:type
rdfs:label
  • Rifamycin
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Rifamycin
NSC_Code
  • 133100
  • 145604
UMLS_CUI
  • C0035609
CAS_Registry
  • 6998-60-3
Accepted_Therapeutic_Use_For
  • Treatment of traveler's diarrhea
FDA_UNII_Code
  • DU69T8ZZPA
Contributing_Source
  • FDA
Chemical_Formula
  • C37H47NO12
Legacy_Concept_Name
  • Rifamycin
CHEBI_ID
  • CHEBI:26580
FULL_SYN
  • 5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-B)furan-1,11(2h)-dione 21-AcetateSNNCI
  • Rifamycin SVSYNCI
  • M-14CNNCI
  • RIFAMYCINPTFDADU69T8ZZPA
  • RifamycinPTNCI
DEFINITION
  • A natural antibiotic produced by Streptomyces mediterranei, Rifamycin (Ansamycin Family) is a commonly used antimycobacterial drug that inhibits prokaryotic DNA-dependent RNA synthesis and protein synthesis; it blocks RNA-polymerase transcription initiation. Rifamycin has an activity spectrum against Gram-positive and Gram-negative bacteria, but is mainly used against Mycobacterium sp. (especially M. tuberculosis) in association with other agents to overcome resistance. (NCI04)NCI
code
  • C29406
sameAs
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