About: Pentamidine Isethionate     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Pentamidine Isethionate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Antibiotic
  • Organic Chemical
Preferred_Name
  • Pentamidine Isethionate
NSC_Code
  • 620107
UMLS_CUI
  • C0591959
CAS_Registry
  • 140-64-7
FDA_UNII_Code
  • V2P3K60DA2
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to treat infections caused by certain microorganisms. It is also being studied in the treatment of melanoma. It prevents DNA from being copied and may kill cancer cells. It is a type of antifungal agent, a type of antiprotozoal agent, and a type of PRL phosphatase inhibitor.NCI-GLOSS
Chemical_Formula
  • C19H24N4O2.2C2H6O4S
Legacy_Concept_Name
  • Pentamidine_Isethionate
CHEBI_ID
  • CHEBI:7977
FULL_SYN
  • Pentamidine IsethionatePTNCI
  • PentacarinatFBNCI
  • PENTAMIDINE ISETHIONATEPTFDAV2P3K60DA2
  • PentamPTNCI-GLOSSCDR0000630954
  • PentamBRNCI
  • pentamidine isethionatePTNCI-GLOSSCDR0000630952
DEFINITION
  • A synthetic amidine derivative, Pentamidine Isethionate is an antiprotozoal and antifungal agent that appears to interact with the minor groove of AT-rich DNA regions of the pathogen genome, interfering with DNA replication and function. It is effective in the treatment of trypanosomiasis, leishmaniasis, some fungal infections, and Pneumocystis carinii pneumonia in HIV-infected patients. (NCI04)NCI
code
  • C29349
sameAs
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