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AttributesValues
rdf:type
rdfs:label
  • Mirtazapine
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Mirtazapine
UMLS_CUI
  • C0049506
CAS_Registry
  • 61337-67-5
  • 85650-52-8
FDA_UNII_Code
  • A051Q2099Q
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to treat depression. It belongs to the family of drugs called antidepressant agents.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 559298
PDQ_Closed_Trial_Search_ID
  • 559298
Chemical_Formula
  • C17H19N3
Legacy_Concept_Name
  • Mirtazapine
CHEBI_ID
  • CHEBI:6950
FULL_SYN
  • MirtazapinePTNCI
  • mirtazapinePTNCI-GLOSSCDR0000450112
  • RemeronPTNCI-GLOSSCDR0000457960
  • RemeronBRNCI
  • MIRTAZAPINEPTFDAA051Q2099Q
DEFINITION
  • A synthetic tetracyclic derivative of the piperazino-azepines with antidepressant activity. Although its mechanism of action is unknown, mirtazapine enhances central adrenergic and serotonergic transmission, possibly by acting as an antagonist at central presynaptic alpha 2 adrenergic inhibitory autoreceptors and heteroreceptors. This agent is a potent antagonist of 5-hydroxytryptamine type 2 (5-HT2), 5-HT3, and histamine 1 (H1) receptors, and a moderate antagonist of peripheral alpha 1 adrenergic and muscarinic receptors.NCI
code
  • C29265
sameAs
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