About: M A T101 HUMAN T-LYMPHOCYTE     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:DeprecatedClass, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • M A T101 HUMAN T-LYMPHOCYTE
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • M A T101 HUMAN T-LYMPHOCYTE
OLD_PARENT
  • Unclassified Drugs and Chemicals
OLD_KIND
  • Chemicals_and_Drugs_Kind
Concept_Status
  • Retired_Concept
FULL_SYN
  • M A T101 HUMAN T-LYMPHOCYTEPTNCI
DEFINITION
  • A murine monoclonal antibody (also known as T101) directed against T65, an antigen found on cutaneous T cell lymphoma (CTCL) cells and chronic lymphocytic leukemia (CLL) cells as well as normal T lymphocytes. M A T101 human T-lymphocyte binds to T cells that express T65, potentially promoting their removal from the circulation, and may induce a cytotoxic T-cell response against T65-expressing T-cells. This agent may also be conjugated to toxins such as ricin for targeted delivery to T65-expressing T cells. (NCI04)NCI
DesignNote
  • Merged with Monoclonal Antibody T101
code
  • C29182
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