About: Losartan Potassium     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Losartan Potassium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Losartan Potassium
UMLS_CUI
  • C0700492
CAS_Registry
  • 124750-99-8
FDA_UNII_Code
  • 3ST302B24A
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to treat high blood pressure. Cozaar blocks the action of chemicals that make blood vessels constrict (get narrower). It is a type of angiotensin II receptor antagonist.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 640981
PDQ_Closed_Trial_Search_ID
  • 640981
Chemical_Formula
  • C22H22ClN6O.K
Legacy_Concept_Name
  • Losartan_Potassium
FULL_SYN
  • losartan potassiumPTNCI-GLOSSCDR0000589412
  • Losartan PotassiumPTDCP31994
  • CozaarPTNCI-GLOSSCDR0000589411
  • 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol, Monopotassium SaltSNNCI
  • CozaarBRNCI
  • Losartan PotassiumPTNCI
  • LOSARTAN POTASSIUMPTFDA3ST302B24A
  • losartanPTNCI-GLOSSCDR0000560966
DEFINITION
  • The potassium salt of losartan, a non-peptide angiotensin II receptor antagonist with antihypertensive activity. Losartan selectively and competitively binds to the angiotensin II receptor (type AT1) and blocks the binding of angiotensin II to the receptor, thus promoting vasodilatation and counteracting the effects of aldosterone. Converted from angiotensin I by angiotensin-converting enzyme (ACE), angiotensin II stimulates the adrenal cortex to synthesize and secrete aldosterone, decreasing sodium excretion and increasing potassium excretion, and acts as a vasoconstrictor in vascular smooth muscle.NCI
code
  • C29165
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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