About: Lodoxamide Tromethamine     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Lodoxamide Tromethamine
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Lodoxamide Tromethamine
UMLS_CUI
  • C0065148
CAS_Registry
  • 63610-09-3
FDA_UNII_Code
  • 50LV9A548L
Contributing_Source
  • FDA
Chemical_Formula
  • C11H6ClN3O6.2C4H11NO3
Legacy_Concept_Name
  • Lodoxamide_Tromethamide
FULL_SYN
  • Lodoxamide TromethaminePTNCI
  • LODOXAMIDE TROMETHAMINEPTFDA50LV9A548L
  • AlomideBRNCI
DEFINITION
  • The tromethamide salt form of lodoxamide, a synthetic mast cell stabilizing compound with anti-inflammatory activity. Upon administration to the eye, lodoxamide tromethamide inhibits type I immediate hypersensitivity reaction by preventing the antigen-stimulated calcium influx into mast cells, thereby inhibiting release of histamine. Lodoxamide tromethamide also prevents the release of slow-reacting substances of anaphylaxis (SRS-A) and inhibits eosinophil chemotaxis.NCI
code
  • C29160
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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