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AttributesValues
rdf:type
rdfs:label
  • Insulin Lispro
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Insulin Lispro
UMLS_CUI
  • C0293359
CAS_Registry
  • 133107-64-9
FDA_UNII_Code
  • GFX7QIS1II
Contributing_Source
  • FDA
Chemical_Formula
  • C257H383N65O77S6
Legacy_Concept_Name
  • Lispo_Insulin
FULL_SYN
  • INSULIN LISPROPTFDAGFX7QIS1II
  • Insulin LisproPTNCI
  • HumalogBRNCI
DEFINITION
  • A recombinant therapeutic agent which is chemically identical to or similar to endogenous human insulin. In lispro insulin, the amino acid proline at B-28 and the amino acid lysine at B-29 are reversed, resulting in the rapid dissolution of this insulin to a monomer that is absorbed rapidly after subcutaneous administration. Lispro insulin is equipotent to human insulin on a molar basis but its effects are faster and of shorter duration. Endogenous insulin, a pancreatic hormone composed of two polypeptide chains, is important in the normal metabolism of carbohydrates, proteins and fats, promoting glucose utilization and protein synthesis; it has anabolic effects on many types of tissues. (NCI04)NCI
code
  • C29123
sameAs
is sameAs of
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