About: FrSh61 (MEA) VHL33 Peptide     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • FrSh61 (MEA) VHL33 Peptide
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • FrSh61 (MEA) VHL33 Peptide
NSC_Code
  • 725177
UMLS_CUI
  • C1517308
Legacy_Concept_Name
  • FrSh61_MEA_VHL33
FULL_SYN
  • FrSh61 (MEA) VHL33 PeptidePTNCI
  • FrSh61 (MEA) VHL33 PeptideSYNCI
DEFINITION
  • A peptide derived from the tumor suppressor protein Von Hippel-Lindau (VHL). This peptide, sequence: MEAGRPRPCCAR, was constructed based on a frameshift mutation of one of the VHL gene products; the more abundant protein VHLp18(MEA) (where MEA stands for three amino acids, Met-Glu-Ala). Vaccination with FrSh61(MEA)VHL33 peptide may stimulate a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing this VHL mutant protein.NCI
code
  • C29065
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