About: FGF-5:172-176 / 217-220 Peptide     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • FGF-5:172-176 / 217-220 Peptide
rdfs:subClassOf
Has_Target
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • FGF-5:172-176 / 217-220 Peptide
NSC_Code
  • 727257
UMLS_CUI
  • C1517089
Legacy_Concept_Name
  • FGF-5_172-176_217-220_Peptide
FULL_SYN
  • FGF-5:172-176 / 217-220 PeptidePTNCI
DEFINITION
  • A naturally occurring 9-residue peptide of fibroblast growth factor 5 (FGF-5). Recognized by tumor infiltrating cytotoxic T lymphocytes originally isolated from a renal cell carcinoma that overexpressed FGF-5, FGF-5:172-176/217-220 peptide activates various cytotoxic CD8 lymphocytes in an HLA-restricted manner. Overexpressed in several cancer cell lines, FGF-5 is a tumor-associated antigen that may be useful in cancer immunotherapy. (NCI04)NCI
code
  • C29040
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