About: Homidium Chloride     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Homidium Chloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Homidium Chloride
NSC_Code
  • 522843
  • 84423
UMLS_CUI
  • C1516978
CAS_Registry
  • 602-52-8
FDA_UNII_Code
  • 7XPK80D0XV
Contributing_Source
  • FDA
Chemical_Formula
  • C21H20N3.Cl
Legacy_Concept_Name
  • Ethidium_Chloride
FULL_SYN
  • 3,8-Diamino-5-ethyl-6-phenylphenanthridinium ChlorideSNNCI
  • 2,7-diamino-9-phenyl-10-ethylphenanthridinium ChlorideSYNCI
  • Ethidium ChlorideSYNCI
  • Homidium ChloridePTNCI
  • Novidium ChlorideSYNCI
  • HOMIDIUM CHLORIDEPTFDA7XPK80D0XV
DEFINITION
  • The chloride salt of ethidium (a fluorochrome), Ethidium Chloride intercalates within double-stranded nucleic acids, particularly DNA. In molecular biology, the bromide salt of ethidium is used to detect and visualize DNA after electrophoresis or in cytochemical preparations. In veterinary pharmacology, it is used as a trypanosomicide. Ethidium bromide and chloride are toxic substances and potent noncompetitive antagonists of the nicotinic acetylcholine receptor. (NCI04)NCI
DesignNote
  • Intercalates with DNA, causing inhibition of DNA replication and RNA synthesis.
code
  • C29022
is Has_Salt_Form of
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