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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Adapalene
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Adapalene
UMLS_CUI
  • C0165631
CAS_Registry
  • 106685-40-9
Accepted_Therapeutic_Use_For
  • Topical treatment of acne vulgaris
FDA_UNII_Code
  • 1L4806J2QF
Contributing_Source
  • FDA
Chemical_Formula
  • C28H28O3
Legacy_Concept_Name
  • Adapalene
CHEBI_ID
  • CHEBI:31174
FULL_SYN
  • AdapalenePTDCP30033
  • CD271CNNCI
  • ADAPALENEPTFDA1L4806J2QF
  • DifferinBRNCI
  • AdapalenePTNCI
  • 6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acidSNNCI
  • 6-(4-Methoxy-3-tricyclo(3.3.1.13,7)dec-1-ylphenyl)-2-naphthalenecarboxylic AcidSNNCI
DEFINITION
  • A topical retinoid-like compound, chemically similar to vitamin A. Although the exact mechanism of action is unknown, adapalene binds to specific retinoic acid receptors in the nucleus, leading to specific gene expression. This agent stimulates skin growth through modulation of cellular differentiation, inflammatory processes and keratinization of follicular epithelial cells. Adapalene may increase dermal sensitivity to ultraviolet radiation. (NCI04)NCI
code
  • C28989
sameAs
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