About: Diacetylmorphine Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Diacetylmorphine Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Diacetylmorphine Hydrochloride
NSC_Code
  • 302357
UMLS_CUI
  • C0282128
CAS_Registry
  • 1502-95-0
FDA_UNII_Code
  • 8H672SHT8E
Contributing_Source
  • FDA
Chemical_Formula
  • C21H23NO5.HCl
Legacy_Concept_Name
  • Diamorphine_Hydrochloride
FULL_SYN
  • DIACETYLMORPHINE HYDROCHLORIDEPTFDA8H672SHT8E
  • Diamorphine HydrochlorideSYNCI
  • Diacetylmorphine HydrochloridePTNCI
  • Morphinan-3,6alpha-diol, 7,8-didehydro-4,5alpha-epoxy-17-methyl-, Morphine, Diacetate (ester), HydrochlorideSNNCI
  • Heroin HydrochlorideSYNCI
  • Heroine HydrochlorideSYNCI
DEFINITION
  • The hydrochloride salt of a diacetyl derivative of the opiate morphine, a naturally occurring alkaloid extracted from the seedpod of the Asian poppy (Papaver sp.). Once administered, diamorphine (or diacetylmorphine) is rapidly hydrolyzed to 6-monoacetylmorphine (6-MAM) and then to the end-product morphine which binds to opiate receptors located throughout the mammalian nervous and gastrointestinal systems. Inducing a potent analgesia, the use of diamoprhine is often escalated due to a tolerance effect, resulting in abuse that is associated with fatal overdose, abortion, venous sclerosis, and opportunistic infections, among other adverse effects. (NCI04)NCI
code
  • C28958
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