About: Cyproheptadine Hydrochloride     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Cyproheptadine Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Cyproheptadine Hydrochloride
NSC_Code
  • 169911
UMLS_CUI
  • C0354872
CAS_Registry
  • 41354-29-4
Accepted_Therapeutic_Use_For
  • Hypersensitivity reactions
In_Clinical_Trial_For
  • Cachexia, cancer or chemotherapy-induced
FDA_UNII_Code
  • NJ82J0F8QC
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 315774
PDQ_Closed_Trial_Search_ID
  • 315774
Chemical_Formula
  • 2C21H21N.2HCl.3H2O
Legacy_Concept_Name
  • Cyproheptadine_Hydrochloride
CHEBI_ID
  • CHEBI:59695
  • CHEBI:650917
FULL_SYN
  • CYPROHEPTADINE HYDROCHLORIDEPTFDANJ82J0F8QC
  • 4-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine Hydrochloride SesquihydrateSNNCI
  • Cyproheptadine HydrochloridePTNCI
  • PeriactinBRNCI
DEFINITION
  • The hydrochloride salt of a synthetic methyl-piperidine derivative with antihistaminic and anti-serotoninergic properties. Cyproheptadine competes with free histamine (HA) for binding at HA-receptor sites, thereby competitively antagonizing histamine stimulation of HA-receptors in the gastrointestinal tract, large blood vessels, and bronchial smooth muscle. This agent also competes with free serotonin for binding at serotonin receptor sites. Cyproheptadine exhibits anticholinergic and sedative properties and has been shown to stimulate appetite and weight gain. (NCI04)NCI
code
  • C28949
sameAs
is Has_Salt_Form of
is sameAs of
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