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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Cyclodisone
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Cyclodisone
NSC_Code
  • 348948
UMLS_CUI
  • C0056746
CAS_Registry
  • 99591-73-8
Legacy_Concept_Name
  • Cyclodisone
FULL_SYN
  • CyclodisonePTNCI
DEFINITION
  • A cyclic sulfonate ester with potential antineoplastic activity. As an alkylating agent, clyclodisone induces the formation of DNA interstrand crosslinks, DNA strand breaks, and alkali-labile lesions in the DNA of some tumor cell lines. Alkylating agents exert cytotoxic and chemotherapeutic effects by transferring alkyl groups to DNA, thereby damaging DNA and interfering with DNA synthesis and cell division. (NCI04)NCI
code
  • C28899
http://linked.open...y/mesh/hasConcept
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