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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Clomesone
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Clomesone
NSC_Code
  • 338947
UMLS_CUI
  • C0055920
CAS_Registry
  • 88343-72-0
FDA_UNII_Code
  • 2J031W0YZI
Contributing_Source
  • FDA
Chemical_Formula
  • C4H9ClO5S2
Legacy_Concept_Name
  • Clomesone
FULL_SYN
  • Chlorethyl SOSOSYNCI
  • 2-Chloroethyl (methylsulfonyl)methanesulfonateSNNCI
  • CLOMESONEPTFDA2J031W0YZI
  • SRI 6155CNNCI
  • ClomesonePTNCI
DEFINITION
  • The 2-chloroethyl ester of (methylsulfonyl) methanesulfonic acid with potential antineoplastic effects. Acting as a chloroethylating agent, clomesone induces the formation of DNA interstrand crosslinks in some cell lines, and exhibits antitumor activity in some animal models. Alkylating agents exert cytotoxic and, in some cases, chemotherapeutic effects by transferring alkyl groups to DNA, thereby damaging DNA and interfering with DNA synthesis and cell division. (NCI04)NCI
code
  • C28888
http://linked.open...y/mesh/hasConcept
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