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AttributesValues
rdf:type
rdfs:label
  • Azithromycin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Antibiotic
Preferred_Name
  • Azithromycin
NSC_Code
  • 643732
UMLS_CUI
  • C0678143
CAS_Registry
  • 83905-01-5
FDA_UNII_Code
  • F94OW58Y8V
Contributing_Source
  • FDA
Legacy_Concept_Name
  • Azithromycin
FULL_SYN
  • AzithromycinPTNCI
  • (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[(3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadeSNNCI
  • AZITHROMYCIN, UNSPECIFIED FORMPTFDAF94OW58Y8V
  • XZ-450CNNCI
  • N-methyl-11-aza-10-deoxy-10-dihydroerythromycin ASNNCI
  • AzaSiteBRNCI
  • CP 62993CNNCI
  • (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[(3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadPTDCP50001
  • ZithromaxBRNCI
DEFINITION
  • An azalide, derived from erythromycin, and a member of a subclass of macrolide antibiotics with bacteriocidal and bacteriostatic activities. Azithromycin reversibly binds to the 50S ribosomal subunit of the 70S ribosome of sensitive microorganisms, thereby inhibiting the translocation step of protein synthesis, wherein a newly synthesized peptidyl tRNA molecule moves from the acceptor site on the ribosome to the peptidyl (donor) site, and consequently inhibiting RNA-dependent protein synthesis leading to cell growth inhibition and cell death.NCI
code
  • C28844
sameAs
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