About: MART-1 Antigen

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	MART-1 Antigen
rdfs:subClassOf	Vaccine Antigen
Semantic_Type	Amino Acid, Peptide, or Protein Immunologic Factor
Preferred_Name	MART-1 Antigen
UMLS_CUI	C1522481
In_Clinical_Trial_For	Melanoma
ALT_DEFINITION	A protein found on normal melanocytes (cells that make the pigment melanin) in the skin and in the retina. It is also found on most melanomas (cancers that begin in melanocytes). Vaccines using pieces of the MART-1 antigen are being studied for their ability to boost the immune response to cancer cells in patients with melanoma.NCI-GLOSS
PDQ_Open_Trial_Search_ID	42205
PDQ_Closed_Trial_Search_ID	42205
Legacy_Concept_Name	MART-1_Antigen
FULL_SYN	MLANA ProteinSYNCI MART-1 AntigenPTNCI Antigen LB39-AASYNCI Antigen SK29-AASYNCI Melan-A ProteinSYNCI MART-1 antigenPTNCI-GLOSSCDR0000486448 MART1SYNCI MLANASYNCI MART-1SYNCI Melan ASYNCI Melan-ASYNCI Melanoma Antigen Recognized by T-Cells 1SYNCI MART-1 Tumor AntigenSYNCI
DEFINITION	A tumor-associated melanocytic differentiation antigen. Vaccination with MART-1 antigen may stimulate a host cytotoxic T-cell response against tumor cells expressing the melanocytic differentiation antigen, resulting in tumor cell lysis. (NCI04)NCI
code	C28724
sameAs	MART-1 Antigen
is someValuesFrom of	nodeID://b645169 nodeID://b646213 nodeID://b647669 nodeID://b647688 nodeID://b647692 nodeID://b647714 nodeID://b647723 nodeID://b673542 nodeID://b673734 nodeID://b673739 nodeID://b673747 nodeID://b673750 nodeID://b673760 nodeID://b673764 nodeID://b673773 nodeID://b673780 nodeID://b673782 nodeID://b682369 nodeID://b682371 nodeID://b683543 nodeID://b683750 nodeID://b688058 nodeID://b688064 nodeID://b689381 nodeID://b725919 nodeID://b725933 nodeID://b725937 nodeID://b725940 nodeID://b725946 nodeID://b725949 nodeID://b725966 nodeID://b725969 nodeID://b725978 nodeID://b725989 nodeID://b725994 nodeID://b725999 nodeID://b726010 nodeID://b726012 nodeID://b726016 nodeID://b726017 nodeID://b726020 nodeID://b726026 nodeID://b726029 nodeID://b726035 nodeID://b726039
is Has_Target of	27-35(27L):MART-1 Peptide Anti-MART-1 TCR Retroviral Vector-Transduced Autologous TIL Autologous Anti-MART-1 F5 T-Cell Receptor Gene-Engineered Peripheral Blood Lymphocytes
is sameAs of	MART-1 Antigen

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