About: Recombinant KSA Glycoprotein     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Recombinant KSA Glycoprotein
rdfs:subClassOf
Is_Related_To_Endogenous_Product
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Immunologic Factor
Preferred_Name
  • Recombinant KSA Glycoprotein
UMLS_CUI
  • C1527244
PDQ_Open_Trial_Search_ID
  • 43440
PDQ_Closed_Trial_Search_ID
  • 43440
Legacy_Concept_Name
  • Recombinant_KSA_Glycoprotein
FULL_SYN
  • EGPSYNCI
  • KSA GlycoproteinSYNCI
  • GA733SYNCI
  • Recombinant KSA GlycoproteinPTNCI
  • Ep-CAMSYNCI
  • CO17-1ASYNCI
DEFINITION
  • A recombinant counterpart of tumor-associated KSA antigen (Ep-CAM), a type-I transmembrane glycoprotein cellular adhesion molecule with a molecular mass of 40 kDa, overexpressed on the majority of tumor cells of most human epithelia in a of variety of tumor tissues such as stomach, colon, pancreas, gall bladder, bile duct, mammary gland, breast, and lung carcinoma. It has been suggested to be involved in the differentiation, growth, and organization of epithelial cells within tissues under normal physiological conditions. The antigen has been used as a target for diagnosis and for passive and active immunotherapy of colorectal cancer. Immunization with KSA Glycoprotein elicits both humoral and Th1-associated cellular immune responses.NCI
code
  • C28721
is someValuesFrom of
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