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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Laniquidar
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Laniquidar
UMLS_CUI
  • C0916124
CAS_Registry
  • 197509-46-9
FDA_UNII_Code
  • K3FRN4DDOY
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance that is being studied for its ability to make cancer cells respond to drugs to which they have become resistant. It belongs to the family of drugs called multidrug resistance inhibitors.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 38526
PDQ_Closed_Trial_Search_ID
  • 38526
Chemical_Formula
  • C37H36N4O3
Legacy_Concept_Name
  • Laniquidar
FULL_SYN
  • R101933PTNCI-GLOSSCDR0000045068
  • R101933CNNCI
  • LANIQUIDARPTFDAK3FRN4DDOY
  • LaniquidarPTNCI
DEFINITION
  • A stereoisomer of verapamil and third-generation P-glycoprotein inhibitor. Laniquidar inhibits the drug efflux pump P-glycoprotein, resulting in higher concentrations of antineoplastic agents in tumor cells that are multi-drug resistant due to the overexpression of P-glycoprotein. (NCI04)NCI
code
  • C28698
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