About: Globo-H-GM2-Lewis-y-MUC1-32(aa)-sTn(c)-TF(c)-Tn(c)-KLH Conjugate Vaccine     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Globo-H-GM2-Lewis-y-MUC1-32(aa)-sTn(c)-TF(c)-Tn(c)-KLH Conjugate Vaccine
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
  • Immunologic Factor
Preferred_Name
  • Globo-H-GM2-Lewis-y-MUC1-32(aa)-sTn(c)-TF(c)-Tn(c)-KLH Conjugate Vaccine
UMLS_CUI
  • C1134578
In_Clinical_Trial_For
  • Breast cancer recurrence -- Temporarily closed.
PDQ_Open_Trial_Search_ID
  • 38552
PDQ_Closed_Trial_Search_ID
  • 38552
Legacy_Concept_Name
  • Globo-H-GM2-Lewis-y-MUC1-32_aa_sTn_c_TF_c_Tn_c_KLH_Conjugate_Vaccine
FULL_SYN
  • Globo-H-GM2-Lewis-y-MUC1-32(aa)-sTn(c)-TF(c)-Tn(c)-KLH Conjugate VaccinePTNCI
DEFINITION
  • A heptavalent vaccine consisting of the tumor-associated carbohydrate antigens globohexaosylceramide (globo-H), GM2, Lewis-y, MUC1-32(aa), sTn(c), TF(c), and Tn(c) conjugated with keyhole limpet hemocyanin (KLH), an immunomodulator. This vaccine may induce the production of IgG and IgM antibodies and an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumors expressing these antigens. (NCI04)NCI
code
  • C28551
is someValuesFrom of
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