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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • ONYX-015
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • ONYX-015
NSC_Code
  • 688653
UMLS_CUI
  • C0678040
ALT_DEFINITION
  • A modified cold virus that selectively grows in and destroys certain types of cancer cells and leaves normal cells undamaged.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 43035
PDQ_Closed_Trial_Search_ID
  • 43035
Legacy_Concept_Name
  • ONYX-015
FULL_SYN
  • E1B 55kDa mutant adenovirus dl1520SYNCI
  • E1B-Attenuated AdenovirusSYNCI
  • ONYX-015PTNCI-GLOSSCDR0000045994
  • CI-1042CNNCI
  • ONYX-015CNNCI
  • ONYX-015PTNCI
DEFINITION
  • An E1B-55kDa-deleted adenovirus that is able to selectively replicate in and lyse TP53-deficient human tumor cells. After tumor cell lysis, released viruses infect neighboring tumor cells, tripping a chain of ONYX-015-mediated tumor cell cytotoxicity. (NCI04)NCI
code
  • C2830
http://linked.open...y/mesh/hasConcept
is someValuesFrom of
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