About: Verpasep Caltespen     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Verpasep Caltespen
rdfs:subClassOf
Has_Target
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Verpasep Caltespen
NSC_Code
  • 713219
UMLS_CUI
  • C1327844
CAS_Registry
  • 295371-00-5
In_Clinical_Trial_For
  • Cervical intraepithelial neoplasia; respiratory papillomatosis
FDA_UNII_Code
  • Z7T0JI2E2I
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance that is being studied in the prevention of cancer. It belongs to the family of drugs called fusion proteins.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 269165
PDQ_Closed_Trial_Search_ID
  • 269165
Legacy_Concept_Name
  • HspE7
FULL_SYN
  • HPV 16 E7/HSP65 VaccineSYNCI
  • Bovine HSP fusion with E7 of HPV16SYNCI
  • HspE7SYDTPNSC0713219
  • HspE7 Therapeutic VaccinePTDCP20390
  • HspE7ABNCI
  • SGN-00101SYDTPNSC0713219
  • Verpasep CaltespenPTNCI
  • HPV E7 Peptide Epitope VaccineSYNCI
  • VERPASEP CALTESPENPTFDAZ7T0JI2E2I
  • SGN-00101PTNCI-GLOSSCDR0000306516
  • SGN-00101CNNCI
DEFINITION
  • A recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from Mycobacterium bovis, and the human papilloma viral (HPV) protein E7. Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be used to design vaccines against a number of different cancers. E7 protein is involved in carcinogenesis of anal and cervical tumors, and represents a tumor antigen that may be specifically targeted by lymphocytes. (NCI04)NCI
code
  • C2811
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