About: MART-1:26-35(27L) Peptide Vaccine     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • MART-1:26-35(27L) Peptide Vaccine
rdfs:subClassOf
Has_Target
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • MART-1:26-35(27L) Peptide Vaccine
NSC_Code
  • 709401
UMLS_CUI
  • C1518107
PDQ_Open_Trial_Search_ID
  • 599670
PDQ_Closed_Trial_Search_ID
  • 599670
Legacy_Concept_Name
  • MART-1_26-35_27L
FULL_SYN
  • MART-1:26-35 (27L)SYNCI
  • MART-1:26-35(27L) Peptide VaccinePTNCI
DEFINITION
  • A peptide-based cancer vaccine consisting of amino acid residues 26 through 35 of MART-1 (melanoma antigen recognized by T-cells-1) with a leucine substitution at amino acid position 27 to improve immunogenicity. Upon administration, MART-1:26-35(27L) peptide vaccine may induce a cytotoxic T-lymphocyte (CTL) response against MART-1-expressing tumor cells, resulting in decreased tumor growth. The tumor-associated antigen (TAA) MART-1 may be overexpressed on melanoma cancer cells.NCI
code
  • C2772
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