About: Poly Microsphere Encapsulated HER2/neu Oral Vaccine     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Poly Microsphere Encapsulated HER2/neu Oral Vaccine
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
  • Immunologic Factor
Preferred_Name
  • Poly Microsphere Encapsulated HER2/neu Oral Vaccine
UMLS_CUI
  • C1514193
Legacy_Concept_Name
  • Poly_Microsphere_Encapsulated_HER2_neu_Oral_Vaccine
FULL_SYN
  • Poly Microsphere Encapsulated HER2/neu Derived p365-377 Peptide Oral VaccineSYNCI
  • Poly Microsphere Encapsulated HER2/neu Oral VaccinePTNCI
DEFINITION
  • A cancer vaccine consisting of Her2/neu peptides incorporated into microspheres of poly (lactide-co-glycolide) (PLGA), a biodegradable polymer. Poly microsphere encapsulated HER2/neu oral vaccine has been investigated for use in immunotherapy for tumors positive for HER-2/neu, a tumor associated antigen that is overexpressed in various cancers, including breast and ovarian cancer. (NCI04)NCI
DesignNote
  • HER2/neu derived p365-377 peptides incorporated into polyactide-cp-glycolide (PLG) microspheres
code
  • C2718
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