About: Recombinant Vaccinia-TRICOM Vaccine     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Recombinant Vaccinia-TRICOM Vaccine
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
  • Virus
Preferred_Name
  • Recombinant Vaccinia-TRICOM Vaccine
NSC_Code
  • 708039
UMLS_CUI
  • C1099097
In_Clinical_Trial_For
  • Metastatic Melanoma.
ALT_DEFINITION
  • A cancer vaccine made with a form of a vaccinia virus that does not cause disease in humans. It is being studied in the treatment of some types of cancer. The virus is changed in the laboratory to make human proteins that may help immune cells in the body kill tumor cells.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 38659
PDQ_Closed_Trial_Search_ID
  • 38659
Legacy_Concept_Name
  • Vaccinia-TRICOM_Vaccine
FULL_SYN
  • Recombinant Vaccinia-TRICOM VaccinePTNCI
  • Vaccinia-TRICOMSYNCI
  • recombinant vaccinia-TRICOM vaccinePTNCI-GLOSSCDR0000572228
  • rV-TRICOMPTNCI-GLOSSCDR0000572227
  • vaccinia-TRICOM vaccinePTNCI-GLOSSCDR0000543385
  • rV-TRICOMSYNCI
DEFINITION
  • A vaccine consisting of recombinant vaccinia virus encoding a TRIad of COstimulatory Molecules (B7-1, ICAM-1, and LFA-3; also called TRICOM). Vaccination with recombinant vaccinia-TRICOM vaccine stimulates the host immune system to mount a non-specific T-cell response. With the addition of a tumor-associated antigen peptide, this vaccine may enhance a tumor-specific immune response.NCI
code
  • C2685
http://linked.open...y/mesh/hasConcept
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