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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Zileuton
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Zileuton
NSC_Code
  • 730712
UMLS_CUI
  • C0081408
CAS_Registry
  • 111406-87-2
Accepted_Therapeutic_Use_For
  • Prevention and Chronic treatment of Asthma
In_Clinical_Trial_For
  • Preventing Lung Cancer in Patients with Bronchial Dysplasia
FDA_UNII_Code
  • V1L22WVE2S
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance that is used to prevent asthma symptoms and that is being studied in the prevention of lung cancer. It belongs to the family of drugs called leukotriene blockers.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 285649
PDQ_Closed_Trial_Search_ID
  • 285649
Chemical_Formula
  • C11H12N2O2S
Legacy_Concept_Name
  • Zileuton
CHEBI_ID
  • CHEBI:10112
FULL_SYN
  • N-(1-Benzo[b]thien-2-ylethyl)-N-hydroxyureaSNNCI
  • ZILEUTONPTFDAV1L22WVE2S
  • ZyfloBRNCI
  • (+-)-N-Hydroxy-N-(1-benzo[b]thien-2-ylethyl)-ureaSNNCI
  • ZileutonPTNCI
  • zileutonPTNCI-GLOSSCDR0000305998
  • ZileutonPTDCP20007
DEFINITION
  • A synthetic derivative of hydroxyurea with antiasthmatic properties. The leukotriene inhibitor zileuton blocks 5-lipoxygenase, which catalyzes the formation of leukotrienes from arachidonic acid; causes bronchodilation; decreases bronchial mucous secretion and edema; and may prevent or decrease the symptoms of asthma. (NCI04)NCI
code
  • C26667
sameAs
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