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AttributesValues
rdf:type
rdfs:label
  • EP-2101
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • EP-2101
UMLS_CUI
  • C1327951
In_Clinical_Trial_For
  • stage IIB or IIIA non-small cell lung cancer and stage III colon cancer.
ALT_DEFINITION
  • A substance that is being studied as a treatment for cancer. It belongs to the family of drugs called cancer vaccines.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 301640
PDQ_Closed_Trial_Search_ID
  • 301640
Legacy_Concept_Name
  • EP-2101
FULL_SYN
  • EP-2101PTNCI-GLOSSCDR0000306497
  • EP-2101CNNCI
  • EP-2101PTNCI
DEFINITION
  • A proprietary cancer DNA vaccine that contains multiple natural and modified epitopes derived from the four tumor associated antigens, CEA, HER2/neu, p53, and MAGE 2/3. EP-2101 also includes CAP1-6D, a heteroclitic CEA analog, and PADRE, a proprietary universal T-cell epitope that serves to enhance the immunogenicity of the epitopes. This agent has been shown to elicit cytotoxic T-lymphocyte responses against tumor cells expressing these multiple epitopes. (NCI04)NCI
code
  • C26645
is someValuesFrom of
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