About: Fibrin Sealant     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Fibrin Sealant
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Fibrin Sealant
UMLS_CUI
  • C0947703
Accepted_Therapeutic_Use_For
  • Cardiovascular Surgery; Colostomy Closure; Congenital Heart Defects; Coronary Artery Bypass Grafting; Mediastinal Bleeding; Microvascular Bleeding; Splenic Trauma.
In_Clinical_Trial_For
  • Reduce Lymphedema Incidence After Lymph Node Dissection in Patients with Vulvar Malignancies and Fluid Accumulation after Breast Surgery.
ALT_DEFINITION
  • A substance used during surgery to help heal wounds. It contains proteins found in human blood that cause blood to clot. When fibrin sealant is placed on a wound, a clot forms. Fibrin sealant is being studied as a way to improve healing after lymph node removal in patients with cancer. It is a type of surgical glue.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 38531
PDQ_Closed_Trial_Search_ID
  • 38531
Legacy_Concept_Name
  • Fibrin_Sealant
FULL_SYN
  • Beriplast PBRNCI
  • Beriplast PPTNCI-GLOSSCDR0000044894
  • TISSEEL VH KitBRNCI
  • Fibrin SealantPTNCI
  • fibrin sealantPTNCI-GLOSSCDR0000045069
  • ArtissBRNCI
  • TISSEELBRNCI
DEFINITION
  • A plasma-derived fibrin biomatrix preparation consisting of two separate solutions that are combined on application. The sealer protein solution contains clottable human fibrinogen and bovine aprotinin, a fibrinolysis inhibitor; the thrombin solution contains human thrombin and calcium chloride. When the solutions are combined, a clot is formed, reproducing the final stages of the coagulation cascade.NCI
code
  • C2664
http://linked.open...y/mesh/hasConcept
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