About: Ertumaxomab     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Ertumaxomab
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Immunologic Factor
Preferred_Name
  • Ertumaxomab
UMLS_CUI
  • C1723386
In_Clinical_Trial_For
  • High risk breast cancer
PDQ_Open_Trial_Search_ID
  • 38498
PDQ_Closed_Trial_Search_ID
  • 38498
Legacy_Concept_Name
  • Anti-CD3_x_anti-HER-2-neu_Bispecific_Monoclonal_Antibody
FULL_SYN
  • ErtumaxomabPTNCI
  • Anti-CD3 x anti-HER-2-neu Bispecific Monoclonal AntibodySYNCI
DEFINITION
  • A murine monoclonal antibody with two antigen-recognition sites: one for CD3, an antigen expressed on mature T cells, and one for HER-2-neu, a tumor-associated antigen that promotes tumor growth. Ertumaxomab attaches to CD3-expressing T cells and HER-2-neu-expressing tumor cells, selectively cross-linking tumor and immunologic cells which results in the recruitment of cytotoxic T cells to the T cell/tumor cell aggregate.NCI
code
  • C2658
http://linked.open...y/mesh/hasConcept
is someValuesFrom of
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