About: Dendritic Cell-Autologous Lung Tumor Vaccine     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Dendritic Cell-Autologous Lung Tumor Vaccine
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
  • Immunologic Factor
Preferred_Name
  • Dendritic Cell-Autologous Lung Tumor Vaccine
UMLS_CUI
  • C1327750
PDQ_Open_Trial_Search_ID
  • 256453
PDQ_Closed_Trial_Search_ID
  • 256453
Legacy_Concept_Name
  • Dendritic_Cell-Autologous_Lung_Tumor_Vaccine
FULL_SYN
  • Dendritic Cell-Autologous Lung Tumor VaccinePTNCI
  • DCVax-LungSYNCI
DEFINITION
  • A cancer vaccine consisting of lymphocytes harvested from a patient with lung cancer and induced to become antigen-presenting cells (APCs) known as dendritic cells. The dendritic cells are transduced with the gene encoding an antigen specific to the patient's cancer and then returned to the patient. In the host, the altered cells stimulate the immune system to mount a primary T cell response against lung tumor cells expressing the target antigen. Dendritic cell-autologous lung tumor vaccines have been investigated for use in cancer immunotherapy. (NCI04)NCI
code
  • C26446
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