About: Lysosomal-Associated Membrane Protein 3

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About: Lysosomal-Associated Membrane Protein 3 Goto Sponge NotDistinct Permalink

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Attributes	Values
rdf:type	Class
rdfs:label	Lysosomal-Associated Membrane Protein 3
rdfs:subClassOf	Transmembrane Protein nodeID://b687852 nodeID://b687853 nodeID://b687854 nodeID://b687855 nodeID://b687856 nodeID://b687857 nodeID://b687858 nodeID://b687859 nodeID://b687860 nodeID://b687861 nodeID://b687862 nodeID://b687863 nodeID://b687864 nodeID://b687865
OMIM_Number	605883
Semantic_Type	Amino Acid, Peptide, or Protein Biologically Active Substance
Preferred_Name	Lysosomal-Associated Membrane Protein 3
UMLS_CUI	C1308703
Legacy_Concept_Name	Lysosomal-Associated_Membrane_Protein-3
FULL_SYN	LAMP3 ProteinSYNCI TSC403 ProteinSYNCI LAMP3SYNCI Lysosome-Associated Membrane Glycoprotein, Dendritic Cell-SpecificSYNCI Lysosomal-Associated Membrane Protein 3PTNCI
Swiss_Prot	O94781
DEFINITION	Expressed in appendix, thymus, lymph node, lung, and spleen and encoded by human LAMP3 Gene (LAMP Family), Lysosomal-Associated Membrane Protein 3 is likely involved in antigen processing by lymphoid dendritic cells that capture antigens, differentiate, and induce T-cell responses. Expression increases in mature interdigitating dendritic cells in T-cell areas. A 416-amino acid 70- to 90-kD type I integral membrane protein (larger than predicted, 44-kD), DCLAMP contains N-and O-glycosylation sites, a LAMP domain, a large extracellular domain, a transmembrane domain, and a 10-amino acid cytoplasmic domain containing a conserved GY lysosomal targeting motif. Expression is up regulated in carcinomas of esophagus, colon, rectum, ureter, stomach, breast, fallopian tube, thyroid, and parotid tissues. (from LocusLink, Swiss-Prot, OMIM, and NCI)NCI
code	C26340
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0294693

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