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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Valganciclovir
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
  • Nucleic Acid, Nucleoside, or Nucleotide
Preferred_Name
  • Valganciclovir
UMLS_CUI
  • C0909381
CAS_Registry
  • 175865-60-8
Accepted_Therapeutic_Use_For
  • Cytomegalovirus retinitis
In_Clinical_Trial_For
  • Cytomegalovirus infections; multicentric Castleman's disease; non-HIV-associated Kaposis sarcoma
FDA_UNII_Code
  • GCU97FKN3R
Contributing_Source
  • FDA
ALT_DEFINITION
  • An antiviral agent that is being studied as a treatment for AIDS-related cytomegalovirus. It is changed in the body to ganciclovir.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 38289
PDQ_Closed_Trial_Search_ID
  • 38289
Legacy_Concept_Name
  • Valganciclovir
CHEBI_ID
  • CHEBI:63635
FULL_SYN
  • VALGANCICLOVIRPTFDAGCU97FKN3R
  • ValganciclovirPTNCI
  • L-Valine, 2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)-3-hydroxypropyl EsterSNNCI
  • valganciclovirPTNCI-GLOSSCDR0000045013
DEFINITION
  • A synthetic prodrug of ganciclovir, a nucleoside analogue of 2'-deoxyguanosine, with antiviral activity. After phosphorylation, valganciclovir is incorporated into DNA, resulting in inhibition of viral DNA polymerase, viral DNA synthesis, and viral replication. (NCI04)NCI
code
  • C2629
sameAs
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