About: Heterotrimeric G Protein Subunit Gene     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Heterotrimeric G Protein Subunit Gene
rdfs:subClassOf
Semantic_Type
  • Gene or Genome
Preferred_Name
  • Heterotrimeric G Protein Subunit Gene
UMLS_CUI
  • C1334000
Legacy_Concept_Name
  • Heterotrimeric_G_Protein_Subunit_Gene
FULL_SYN
  • Heterotrimeric G Protein Subunit GenePTNCI
Gene_Encodes_Product
  • Heterotrimeric G Protein
DEFINITION
  • Heterotrimeric G Protein Subunit Genes encode Heterotrimeric G Protein signal transducers, attached to the plasma membrane, that connect seven transmembrane cell surface G-protein coupled receptors to intracellular signal transduction effectors and pathways. Inactive G proteins consist of alpha/beta/gamma complexes that signal as dissociated GTP-bound alpha subunit or the beta/gamma complex. GTP hydrolysis by the inherent GTPase reverts the alpha subunit to its inactive (heterotrimeric) form. Receptors coupled to G proteins communicate signals from hormones, neurotransmitters, chemokines, and autocrine and paracrine factors. (NCI)NCI
code
  • C26191
is rdfs:subClassOf of
is someValuesFrom of
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