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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • INS316
rdfs:subClassOf
Semantic_Type
  • Indicator, Reagent, or Diagnostic Aid
Preferred_Name
  • INS316
UMLS_CUI
  • C0935963
CAS_Registry
  • 266356-22-3
In_Clinical_Trial_For
  • Adjuvant for Diagnosis of Lung Cancer.
ALT_DEFINITION
  • A substance being studied in the diagnosis of lung diseases, including lung cancer. It helps bring up a sample of mucus from deep in the lungs and improves the quality of the sample for testing. It is a type of nucleoside triphosphate.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 38185
PDQ_Closed_Trial_Search_ID
  • 38185
Legacy_Concept_Name
  • INS316
FULL_SYN
  • UTP SolutionSYNCI
  • INS316PTNCI-GLOSSCDR0000390287
  • INS316PTNCI
  • Uridine 5-Triphosphate SolutionSYNCI
DEFINITION
  • A short-acting, aerosolized uridine 5-triphosphate (UTP) solution used as a diagnostic aid for lung cancer. INS316 appears to improve sputum expectoration mediated through the P2Y2 receptor, a nucleotide receptor expressed in human airway epithelial cells and some other tissues. UTP binding to the P2Y2 receptor triggers signal transduction that leads to chloride ion secretion, thereby resulting in mucociliary clearance of airway.NCI
code
  • C2613
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