About: Technetium Tc 99m Epratuzumab     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Technetium Tc 99m Epratuzumab
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Technetium Tc 99m Epratuzumab
UMLS_CUI
  • C0678085
PDQ_Open_Trial_Search_ID
  • 43086
PDQ_Closed_Trial_Search_ID
  • 43086
Legacy_Concept_Name
  • Technetium_Tc_99m_Epratuzumab
FULL_SYN
  • Technetium Tc 99m EpratuzumabPTNCI
  • Tc 99m Monoclonal Antibody LL2SYNCI
  • Technetium Tc 99m LL2 Monoclonal AntibodySYNCI
  • Technetium Tc 99m Monoclonal Antibody LL2SYNCI
  • Tc 99m LL2ABNCI
DEFINITION
  • A radioimmunoconjugate of the humanized IgG1 monoclonal antibody (MoAb) LL2 labeled with Technetium 99m (Tc-99m). Epratuzumab (MoAb LL2) recognizes CD22, a B-lymphocyte-restricted antigen expressed as a cytoplasmic protein in progenitor B cells, and as a cell surface protein in mature B cells. Tc-99m epratuzumab delivers gamma emission Tc-99m directly to B-lymphocyte lineage cells, thereby the agent may be used for diagnostic or treatment purposes.NCI
code
  • C2574
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