About: Human Papillomavirus 16 E7 Peptide/Padre 965.10

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About: Human Papillomavirus 16 E7 Peptide/Padre 965.10 Goto Sponge NotDistinct Permalink

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Attributes	Values
rdf:type	Class
rdfs:label	Human Papillomavirus 16 E7 Peptide/Padre 965.10
rdfs:subClassOf	Human Papilloma Virus Vaccine nodeID://b680702 nodeID://b680703 nodeID://b680704
Semantic_Type	Pharmacologic Substance
Preferred_Name	Human Papillomavirus 16 E7 Peptide/Padre 965.10
NSC_Code	679904
UMLS_CUI	C0338214
PDQ_Open_Trial_Search_ID	42276
PDQ_Closed_Trial_Search_ID	42276
Legacy_Concept_Name	Human_Papillomavirus_16_E7_Peptide-Padre_965_10
FULL_SYN	Human Papillomavirus 16 E7 Peptide/Padre 965.10PTNCI HPV16 E7/PADRE 965.10SYNCI Lipidated HPV-16 E7/Padre-965.10SYNCI
DEFINITION	A synthetic agent derived from human papillomavirus (HPV) E7 nuclear protein which is used to produce vaccines against HPV infection and HPV-related neoplasms. HPV E7 oncogenic protein binds the retinoblastoma tumor suppressor protein, pRB, as well as a number of other cellular proteins, and serves as a transcriptional activator. This protein is important in the induction and maintenance of cellular transformation and is co-expressed in the majority of HPV-containing carcinomas. PADRE(R) is a proprietary family of molecules that enhances the immune systems response against an administered immunogen such as the HPV E7 nuclear protein. (NCI04)NCI
code	C2569

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