About: GVAX Prostate Cancer Vaccine     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • GVAX Prostate Cancer Vaccine
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
  • Immunologic Factor
Preferred_Name
  • GVAX Prostate Cancer Vaccine
UMLS_CUI
  • C0796615
In_Clinical_Trial_For
  • Advanced-Stage; Hormone Refractory; Prostate Cancer.
PDQ_Open_Trial_Search_ID
  • 43459
PDQ_Closed_Trial_Search_ID
  • 43459
Legacy_Concept_Name
  • GVAX_Prostate_Cancer_Vaccine
FULL_SYN
  • Allogenic Prostate GVAXSYNCI
  • GVAX ProstateSYNCI
  • Prostate Cancer Vaccine, GM-CSF Gene TransducedSYNCI
  • GM-CSF Gene Transduced Allogeneic Prostate Cancer VaccineSYNCI
  • GVAX Allogenic Prostate Cancer VaccineSYNCI
  • GVAX Prostate Cancer VaccinePTNCI
  • GVAX Allogeneic Prostate Cancer VaccineSYNCI
  • Prostate Cancer Vaccine, GVAXSYNCI
  • Allogeneic Prostate Cancer Vaccine, GM- CSF Gene TransducedSYNCI
  • GM-CSF prostate cancer vaccineSYNCI
DEFINITION
  • A whole cell vaccine expressing human granulocyte macrophage-colony stimulating factor (GM-CSF) with potential antineoplastic activity. Tumor cells from prostate cancer patients are harvested and then genetically modified to secrete GM-CSF, an immune stimulatory growth factor that plays a key role in stimulating the body's immune responses against tumor cells. Because the vaccine is derived from allogenic cells, it has demonstrated a favorable side effect profile than other approaches of delivering long-lasting GM-CSF.NCI
code
  • C2525
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