About: Recombinant Vaccinia DF3/MUC1 Vaccine     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Recombinant Vaccinia DF3/MUC1 Vaccine
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
  • Immunologic Factor
Preferred_Name
  • Recombinant Vaccinia DF3/MUC1 Vaccine
UMLS_CUI
  • C0796497
In_Clinical_Trial_For
  • Metastatic Breast Cancer.
PDQ_Open_Trial_Search_ID
  • 43350
PDQ_Closed_Trial_Search_ID
  • 43350
Legacy_Concept_Name
  • Recombinant_Vaccinia_DF3_MUC1_Vaccine
FULL_SYN
  • rV-DF3/MUC1ABNCI
  • Recombinant Vaccinia DF3/MUC1 VaccinePTNCI
DEFINITION
  • A vaccinia virus based vaccine expressing human tumor associated epithelial mucin (DF3 antigen; MUC1). MUC1 antigen, a membrane bound glycoprotein expressed by most glandular and ductal epithelial cells, is overexpressed in various tumors such as breast, prostate, and ovarian cancers. This vaccine could be used in development of immunotherapeutics against cancers expressing MUC1.NCI
code
  • C2510
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