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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Antineoplaston Agent
rdfs:subClassOf
Semantic_Type
  • Chemical Viewed Functionally
Preferred_Name
  • Antineoplaston Agent
UMLS_CUI
  • C1516025
ALT_DEFINITION
  • A substance isolated from normal human blood and urine that is being tested as a type of treatment for some tumors and AIDS.NCI-GLOSS
Legacy_Concept_Name
  • Antineoplaston_Agent
FULL_SYN
  • AntineoplastonsSYNCI
  • antineoplastonPTNCI-GLOSSCDR0000046149
  • Antineoplaston AgentPTNCI
DEFINITION
  • A peptide, amino acid derivative, and/or organic acid extracted from blood serum, urine, or synthesized chemically, that inhibits the methylation of nucleic acids and the incorporation of L-glutamine into tumor-cell proteins. These agents also intercalate into DNA, leading to cell cycle arrest in the G1 phase and inhibition of mitosis and terminal cell differentiation. In addition, antineoplastons may inhibit RAS oncogene expression and activate the tumor suppressor gene p53, resulting in cell differentiation and apoptosis. (NCI04)NCI
code
  • C2500
is rdfs:subClassOf of
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