About: Peptide 946-Tetanus Peptide Conjugate Melanoma Vaccine

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About: Peptide 946-Tetanus Peptide Conjugate Melanoma Vaccine Goto Sponge NotDistinct Permalink

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Attributes	Values
rdf:type	Class
rdfs:label	Peptide 946-Tetanus Peptide Conjugate Melanoma Vaccine
rdfs:subClassOf	Melanoma Vaccine
Semantic_Type	Pharmacologic Substance Immunologic Factor
Preferred_Name	Peptide 946-Tetanus Peptide Conjugate Melanoma Vaccine
UMLS_CUI	C0677987
In_Clinical_Trial_For	Melanoma.
PDQ_Open_Trial_Search_ID	42975
PDQ_Closed_Trial_Search_ID	42975
Legacy_Concept_Name	Peptide_946-Tetanus_Peptide_Conjugate_Melanoma_Vaccine
FULL_SYN	Peptide 946-Tetanus Peptide Conjugate Melanoma VaccinePTNCI
DEFINITION	A melanoma peptide vaccine complexed with tetanus toxoid with potential antineoplastic activity. Peptide 946 contains a melanoma-specific epitope recognized by melanoma-specific cytotoxic T lymphocytes (CTL). In addition to the peptide 946 sequence, this vaccine contains tetanus toxin, a protein known to stimulate the induction of CD4+ T lymphocytes; it thereby enhances antigen processing and presentation. Vaccination with the peptide 946-tetanus conjugate melanoma vaccine may produce antibodies as well as elicit a cytotoxic T lymphocyte (CTL) response in tumor cells expressing the 946 epitope, thereby decreasing tumor cell growth.NCI
code	C2467
is someValuesFrom of	nodeID://b682392 nodeID://b693746

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