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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Rasburicase
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Rasburicase
NSC_Code
  • 721631
UMLS_CUI
  • C0937932
CAS_Registry
  • 134774-45-1
Accepted_Therapeutic_Use_For
  • Chemotherapy-induced acute hyperuricemia, treatment and prophylaxis
In_Clinical_Trial_For
  • B-cell leukemia or lymphoma
FDA_UNII_Code
  • 08GY9K1EUO
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to treat high blood levels of uric acid in patients with leukemia, lymphoma, and other types of cancer who are receiving certain types of cancer treatment. It is also being studied in the treatment of other medical conditions. Elitek is a type of recombinant enzyme and a type of urate-lowering drug.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 299001
PDQ_Closed_Trial_Search_ID
  • 299001
Legacy_Concept_Name
  • Rasburicase
FULL_SYN
  • RasburicasePTNCI
  • rasburicasePTNCI-GLOSSCDR0000306513
  • Urate OxidaseSYDTPNSC0671264
  • recombinant urate oxidasePTNCI-GLOSSCDR0000658362
  • Recombinant Urate OxidaseSYNCI
  • ElitekPTNCI-GLOSSCDR0000658361
  • SR-29142PTNCI-GLOSSCDR0000046055
  • ElitekBRNCI
  • SR 29142CNNCI
  • SR-29142CNNCI
  • RASBURICASEPTFDA08GY9K1EUO
DEFINITION
  • A recombinant urate oxidase enzyme isolated from a genetically-modified strain of Saccharomyces cerevisiae. Urate oxidase catalyzes the oxidation of uric acid to the excretable metabolite allantoin, a molecule that is 5-10 times more water-soluble than uric acid. An enzyme that occurs endogenously in most mammals, urate oxidase is not found in humans. (NCI04)NCI
code
  • C2404
sameAs
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