About: GD2-KLH Vaccine     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • GD2-KLH Vaccine
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
  • Immunologic Factor
Preferred_Name
  • GD2-KLH Vaccine
UMLS_CUI
  • C0338229
PDQ_Open_Trial_Search_ID
  • 42296
PDQ_Closed_Trial_Search_ID
  • 42296
Legacy_Concept_Name
  • GD2-KLH_Vaccine
FULL_SYN
  • GD2-KLH VaccinePTNCI
  • KLH-conjugated GD2 Ganglioside VaccineSYNCI
  • Ganglioside GD2-KLHSYNCI
DEFINITION
  • A cancer vaccine containing an epitope of glycosphingolipid GD2 conjugated with the immunostimulant keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. The disialoganglioside GD2 is a tumor-associated antigen expressed on the surface of several cancers, including neuroblastoma medulloblastomas, astrocytomas, melanomas, small-cell lung cancer, osteosarcomas, and other soft tissue sarcomas. Vaccination with GD2-KLH vaccine may elicit antibody production against cells expressing GD2 ganglioside, thereby reducing tumor cell growth.NCI
code
  • C2400
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